Lactated Ringer's solution is a solution that is isotonic with blood and intended for intravenous administration. It may also be given subcutaneously. Lactated Ringer's solution is grouped with intravenous fluids known as "crystalloids" – which include saline and dextrose solutions (compared to the "colloids" which contain larger molecules such as starch or gelatine).
One litre of lactated Ringer's solution contains:
130 mEq of sodium ion = 130 mmol/L
109 mEq of chloride ion = 109 mmol/L
28 mEq of lactate = 28 mmol/L
4 mEq of potassium ion = 4 mmol/L
3 mEq of calcium ion = 1.5 mmol/L
Lactated Ringers has an osmolarity of 273 mOsm/L. The lactate is metabolized into bicarbonate by the liver, which can help correct metabolic acidosis.
Generally, the sodium, chloride, potassium and lactate come from NaCl (sodium chloride), NaC3H5O3
Generally, the sodium, chloride, potassium and lactate come from NaCl (sodium chloride), NaC3H5O3 (sodium lactate), CaCl2 (calcium chloride), and KCl (potassium chloride).
Lactated Ringer's solution is often used for fluid resuscitation after a blood loss due to trauma, surgery, or a burn injury