The following adverse events have also been reported to occur in 1% of sertraline (Zoloft) treated patients suffering from OCD or major depressive disorder, except those already listed. It is important to emphasize that although the events reported occurred during treatment with sertraline, they were not necessarily caused by it. The following events are listed by body system. Body as a whole: back pain, asthenia/weakness, malaise. Cardiovascular system: palpitations, chest pain (unspecified). Gastrointestinal: increased appetite (polyphagia), weight gain. Central and peripheral nervous system: hypertonia, hyperesthesia. Musculoskeletal: myalgia. Psychiatric: yawning, various forms of sexual dysfunction in males or females, not described. Respiratory: rhinitis. Special senses: tinnitus. NOTE: additional reported infrequent side effects (0.1—1% of patients) and rare events (<= 0.1% of patients) in which a causal relationship to sertraline has not been established are listed in the manufacturer's prescribing information. Reports of adverse events temporally associated with sertraline that have been received since market introduction, that are not previously listed and that may have no causal relationship with the drug may also be found in the manufacturer's literature.