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Rifampin recommended for latent TB infection in children in areas of high isoniazid resistance
MedWire News: US researchers are calling for new treatment protocols in children with latent tuberculosis (TB). Rifampin should be considered for any child with nonactive TB arriving from an area with isoniazid-resistance exceeding 11%, according to the team. "It will be important that future latent TB infection guidelines address the possibility of drug resistance in high-risk individuals such as children who are internationally adopted, immigrants, or refugees," write Maria Finnell (Indiana University School of Medicine, Indianapolis) and colleagues in the journal Pediatrics.