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    Clinically Significant Drug Interaction with the Cytochrome P450 Enzyme System

    h4. Introduction Many drugs undergo oxidative biotransformation in order to be transformed from lipophilic to hydrophilic compounds so that they may be more readily eliminated from the body. The cytochrome P450 enzyme system is the major catalyst of oxidative biotransformation reactions involved in drug metabolism. The nomenclature of the cytochrome P450 enzyme system involves grouping the enzymes into families and subfamilies. ...
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